Theme: No-no's
17. Easy orchard pickings : LOW HANGING FRUIT. Forbidden fruit. It all started with the apple.
27. Bankrupt Best Buy competitor : CIRCUIT CITY. Forbidden City, the Chinese imperial palace.
49. Best-selling 2006 memoir subtitled "One Woman's Search for Everything Across Italy, India, and Indonesia" : "EAT PRAY LOVE". Forbidden love which starts a lot of trouble.
65. Groundbreaking 1956 sci-fi film ... or where you might find the ends of 17-, 27- and 49-Across? : FORBIDDEN PLANET. Redux of CED's clip.
Argyle here. And C.C. And two grid spanners.
Across:
1. Jab : POKE
5. Ran, as dye : BLED
9. Cola choice : PEPSI
14. Work with words : EDIT
15. Pervasive glow : AURA
16. Secluded valleys : DELLS
20. Test run : TRIAL
21. Char : SEAR
22. Little tricksters : IMPS
23. "Fat chance!" : "NOT!"
25. "__ the picture" : I GET
33. Approves : OKs
36. Small Chevy model : AVEO
37. Deserve : EARN
38. Copy in fun : MIMIC
40. "__ That Tune": classic game show : NAME
41. Mild oaths : DRATs
43. Full-grown filly : MARE
44. Without a break : ON END
46. Sign that might bode ill : OMEN
47. Heavy amount, as of homework : A TON
48. "Platoon" war zone : NAM
52. Gunshot sound : [BANG!]
54. Toothpaste option : GEL
55. Stand watch for, say : ABET
57. Lira replacement : EURO
61. Is in first place : LEADS
68. Caesar or Brutus : ROMAN
69. Dedicated poems : ODEs
70. Part in a play : ROLE
71. Follows orders : OBEYS
72. Overly inquisitive : NOSY
73. Barbershop sound : SNIP snip snip snip snip snip...
Down:
1. Animal's hide : PELT
2. Scent : ODOR
3. New Zealand bird : KIWI
4. One of two directing brothers : ETHAN COEN. The other is Joel.
5. Prohibit : BAN
6. Hauls with effort : LUGs
7. The "E" in HOMES : ERIE. A mnemonic for remembering Huron, Ontario, Michigan, Erie and Superior Lakes.
8. Comic Carvey : DANA
9. Adobe document suffix : PDF. (Portable Document Format)
10. Bone-chilling : EERIE
11. Spaghetti sauce ingredient : PLUM TOMATO
12. Lose one's footing : SLIP
13. Believers: Suff. : ISTs
18. Felipe of baseball : ALOU. Did you know his name was really Felipe Rojas. The Giants' scout who signed him got it wrong.
19. "True __": Wayne film : GRIT
24. In a dead heat : TIED
26. Athletic center : GYM
27. Popular Pachelbel work : CANON
28. The first Mrs. Trump : IVANA
29. "Isn't my face familiar?" : "REMEMBER ME?"
30. Futurist's deck : TAROT
31. Calf muscle malady : CRAMP
32. Entomb : INTER
34. Big name in Russian ballet : KIROV. The Soviet Ballet in 1934 was named to honor Sergey Kirov, an assassinated revolutionary. Officially, it is now the Mariinsky Ballet.
35. Drama division : SCENE
39. "Please tell me" : "I'M ALL EARS"
42. Stocking tear : SNAG
45. Bear's home : DEN
50. Like much wine and cheese : AGED
51. Holler : YELL
53. Cornered : AT BAY
55. Jackson 5 hair style : AFRO
56. __ tube: TV : BOOB
58. Japanese noodle : UDON. Often in your soup.
59. Make over : REDO
60. Snake eyes pair : ONEs
62. Soon, to a bard : ANON
63. Supermarket section : DELI
64. Dance movement : STEP
66. __ and outs: particulars : INS
67. Aspiring therapist's maj. : PSY. (Psychology)
Argyle